Scientific Program & Video Proceedings

Complete Scientific Program & Abstracts (pdf)


Video Proceedings (all)

The scientific presentations of this symposium were video recorded and released for public viewing through generous sponsorship from the Chiari & Syringomyelia Foundation, which was made possible by the support of The Monkton Institute.


Scientific Program, Day 1 — Monday, June 19th, 2017

Plenary Lecture

Syringomyelia pathophysiology: basic and clinical science, Marcus Stoodley, Australia.


Session A: Syringomyelia

Exchange of fluid between a syrinx and the stenosed spinal subarachnoid space, Chris Bertram, Australia.

Mathematical modelling of spinal CSF dynamics: Human and animal models of Syringomyelia, Serge Cirovic, UK.


Session B: Intrathecal flow and transport, part 1

Interacting fluid compartments of the central nervous system: A holistic mathematical modelling approach, Eleuterio Toro, Italy.

Are monkeys like humans?  Comparison of intrathecal CSF dynamics across mammalian species, Bryn Martin, USA.

Computational modelling of spinal perivascular flow: Relationships between perivascular transport and subarachnoid space pressure, pulse timing and pulse shape, Lynne Bilston, Australia.


Session C: Fluid balance in the brain, part 1

Posture effects on cerebrospinal fluid pressure gradient and dynamics: does normal intracranial pressure has subatmospheric (negative) value? Marijan Klarica, Croatia.

Measuring brain biomechanics in chronically shunted hydrocephalus with MR elastography, Mark Washgul, USA.

Compound CSF disorders: Hypertension, hypotension and ICP monitoring, Mark Luciano, USA.

In vitro modeling of the CSF dynamics study to investigate the etiology of NPH, Anne Benninghaus, Germany


Session D: Intrathecal flow and transport, part 2

Intrathecal bolus: The initial dynamics and solute entrance into the perivascular spaces, Mikhail Ivanovich Papisov, USA.

Darcy-Brinkman model of shear-augmented dispersion in cerebrovascular basement membranes and the spinal subarachnoid space, Keith Sharp, USA.

Pressure gradient estimation in the spinal canal based on in vivo MR measurements, Francis Loth, USA.



Scientific Program, Day 2 — Tuesday, June 20th, 2017

Plenary Lecture

Autodigestion and proteolytic receptor cleavage: Digestive enzymes on the prowl, Prof. Geert W. Schmid-Schoenbein, USA.


Session A: Stroke and Dementia

The role of fluid transport in reperfusion injury post ischemic stroke, Stephen Payne, UK.

Subject-specific multiporoelastic model for exploring the risk factors associated with dementia, Liwei Guo, UK.


Session B: Interstitial and perivascular flows

Simulating the fluid flow of the glymphatic system – extracellular fluid flow, Kent Andre Mardal, Norway.

A bioengineering perspective on the human brain cellular structure: What do we know and what would we need to know, Diane de Zélicourt, Switzerland.

MR imaging and modeling connected perivascular spaces in rodents, Malisa Sarntinoranont, USA.


Session C: Fluid balance in the brain, part 2

Respiratory driven oscillations in CSF and venous and arterial hemodynamics measured with real-time velocity phase mapping, David Feinberg, USA.

CSF and cerebral blood flow: What is a normal flow? Olivier Balédent, France.

Control of active CSF shunts – Is the pulse pressure amplitude a suitable control variable? Marianne Schmid Daners, Switzerland.


Session D: Cranial flows and pressures

Cerebrospinal fluid pressure reduction results in dynamic changes in optic nerve angle on MRI, Amit Saindane, USA.

Differentiating between barrier dysfunction and drainage reduction in CSF protein analysis, Vartan Kurtcuoglu, Switzerland.

Measuring Brain Displacement with DENSE MRI, John Oshinski, USA.




A global, multi-scale mathematical model of the murine fluid systems, including meningeal lymphatic, Christian Contarino, Italy

Flow resistance along basement membranes in the perivascular space of cerebral arteries, Mohammad M. Faghih, USA

The effect of Chiari malformation and syringomyelia on CSF flow: CFD subject-specific models for a cohort of Chiari patients and controls, Robert Lloyd, Australia

Interest of MRI in the investigation of the CSF with the blood flows interactions, Armelle Lokossou, France

Resistance network model of pulsatile flow drivers in rat parenchyma and PVS, Julian Rey, USA