The cerebrospinal fluid (CSF) is vital to the homeostasis of the central nervous system (CNS). This is reflected by its function as a pathway for the neuroendocrine and the immune systems, and by its involvement in various disorders, from hydrocephalus to Alzheimer’s disease. CSF is not a stagnant fluid. Superimposed onto a slow, steady flow from its production to absorption sites is a strong pulsatile component driven indirectly by the cardiac cycle and modulated by respiration. It is intuitively clear that CSF flow is an integral component in CSF function: Transport of neuroendocrine substances, metabolites, cytokines, chemokines and cells of the immune system is influenced by or dependent on flow.
Despite the importance of the cerebrospinal fluid, its dynamics are not well understood. The purpose of the International Cerebrospinal Fluid Dynamics Society (ICFDS) is to bring together scientist worldwide who are actively engaged in research focused on CSF dynamics. The mission of the ICFDS is to offer a platform for scientific exchange to answer the open questions in the field.